Thursday, October 22, 2026

Dermatological Problems in Pregnancy

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SWARAJ HOSPITAL & RESEARCH INSTITUTE
BOLANGIR, ODISHA  •  OBSTETRICS & GYNAECOLOGY CLINICAL PATHWAY SERIES
Clinician Reference Infographic

Dermatological Problems in Pregnancy — Safe Treatment

Skin problems in pregnancy range from harmless physiological changes to conditions that endanger the baby, such as cholestasis, pemphigoid gestationis, and pustular psoriasis. This guide covers normal changes, pregnancy-specific dermatoses, common skin diseases, and safe treatment, using the ITCHING approach.

Skin changes occur in nearly every pregnancy; most are harmless physiological changes (pigmentation, stretch marks, vascular spiders, hair and nail changes)

Four pregnancy-specific dermatoses: atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP), pemphigoid gestationis (PG), and intrahepatic cholestasis of pregnancy (ICP) — plus pustular psoriasis of pregnancy

Itch is the commonest symptom: itch without a rash (especially palms and soles at night) is ICP until proved otherwise — it is the one that can kill the baby

Two things decide management: is there a primary rash (papules, plaques, blisters)? and is the fetus at risk? (ICP, PG, and pustular psoriasis are; AEP and PEP are not)

Never attribute generalised itch in late pregnancy to 'dry skin' before checking liver function tests and fasting or random bile acids
🚨 ACT AT ONCE
Itch on palms and soles, worse at night, no rash — obstetric cholestasis: bile acids and liver tests the same day; risk of stillbirth
Blisters beginning around the navel — pemphigoid gestationis: skin biopsy with direct immunofluorescence; fetal growth scans
Widespread pustules with fever — pustular psoriasis of pregnancy: admit, check calcium and albumin, fetal surveillance
Rash with fever or palm and sole lesions: exclude syphilis, varicella, measles, rubella, drug eruption
🗺️ THE PATHWAY AT A GLANCE
1 · LookIs there a primary rash? Where did it start? (navel, striae, flexures, palms)
2 · TimeGestation at onset, first or later pregnancy, previous skin disease
3 · TestBile acids and liver tests; biopsy with immunofluorescence for blisters; exclude infection
4 · TreatEmollients, topical steroids, antihistamines; specific drugs by diagnosis
5 · WatchFetal growth and wellbeing in ICP, PG, and pustular psoriasis
6 · PlanTiming of delivery, postpartum flares, and recurrence advice
STEP 1 · PHYSIOLOGICAL SKIN CHANGES — common, harmless, reassure
ChangeDetails
PigmentationDarkening of nipples, areola, genitalia, linea nigra; melasma (chloasma) in about 50–70% (face, worse in sun); fades after delivery but may persist — sunscreen with broad-spectrum protection and a hat
Striae gravidarumStretch marks in about 80–90% (abdomen, breasts, thighs); risk higher in young women, family history, large weight gain, big babies; no cream is proven to prevent them; fade to silvery lines
VascularSpider naevi, palmar erythema, varicose veins, haemorrhoids, oedema; gingival swelling and bleeding; pyogenic granuloma (epulis)
HairHair thicker in pregnancy (longer growth phase); telogen effluvium (diffuse shedding) 1–5 months after delivery, recovers in 6–12 months
Nails and glandsBrittle nails, ridging, separation from the nail bed; acne may flare; increased sweating, and reduced apocrine gland activity
Counsel: these are normal; sun protection limits melasma; avoid hydroquinone and tretinoin in pregnancy; treat melasma after delivery if it persists
STEP 2 · PREGNANCY-SPECIFIC DERMATOSES — know the four, and the fifth
🔴 ATOPIC ERUPTION OF PREGNANCY AND POLYMORPHIC ERUPTION
ConditionFeatures and management
Atopic eruption of pregnancy (AEP)Commonest (about half of pregnancy dermatoses); early or mid pregnancy; eczema on flexures (E-type) or itchy papules and nodules (P-type); often a history of atopy; no fetal risk
Treatment of AEPEmollients, mild to moderate topical steroids, antihistamines (chlorphenamine at night; loratadine or cetirizine by day); narrowband ultraviolet B or short oral prednisolone if severe; treat infection (staphylococcus)
Polymorphic eruption of pregnancy (PEP, PUPPP)First pregnancy, third trimester, twins; itchy urticarial papules and plaques that start in the stretch marks of the abdomen and spare the navel; spreads to thighs and limbs; no fetal risk
Treatment of PEPEmollients, moderate to potent topical steroid, antihistamines; oral prednisolone if severe; resolves within days to weeks after delivery; seldom recurs
TopicDetails
What it isRare autoimmune blistering disease (about 1 in 50,000) with antibodies against BP180, a skin basement membrane protein; linked to HLA-DR3 and DR4, Graves disease, and molar pregnancy
FeaturesIntense itch, then urticarial papules and plaques around the navel that spread to limbs and trunk and develop tense blisters; second or third trimester; may flare around delivery
DiagnosisSkin biopsy with direct immunofluorescence (linear C3 along the basement membrane), serum anti-BP180; exclude PEP (which spares the navel and has no antibodies)
Fetal riskPreterm birth, small-for-gestational-age babies, and stillbirth; 10% of newborns have transient blisters
TreatmentPotent topical steroids and antihistamines; oral prednisolone 0.5 mg/kg daily for blisters, reduce slowly after control
MonitoringGrowth scans and fetal surveillance; delivery at 37–38 weeks if no complications, earlier for fetal concern
AfterwardsFlare after delivery in about 75%, resolves in weeks to months; recurs in later pregnancies, usually earlier and more severe
🟡 INTRAHEPATIC CHOLESTASIS OF PREGNANCY (OBSTETRIC CHOLESTASIS)
TopicDetails
FeaturesItch without a primary rash, worse at night and on palms and soles; usually after 28 weeks (can be earlier); excoriations only; dark urine, pale stools, jaundice in a few
WhoAbout 0.7% in the UK, higher in South Asian women; multiple pregnancy, previous ICP, family history, hepatitis C, gallstones
TestsFasting serum bile acids (10 µmol/L or more is abnormal; a non-fasting sample is acceptable) and liver tests (ALT, AST); if normal and the itch persists, repeat weekly; exclude hepatitis, gallstones, pre-eclampsia, HELLP
Fetal riskStillbirth, preterm birth, meconium, fetal distress; risk rises with bile acids, with the highest risk at 100 µmol/L or more
TreatmentUrsodeoxycholic acid 10–15 mg/kg daily in divided doses (relieves itch for many; does not clearly prevent stillbirth); emollients, cooling; vitamin K 10 mg daily if prothrombin time is prolonged
MonitoringBile acids and liver tests weekly; fetal growth scans; cardiotocography does not predict stillbirth
DeliveryBile acids 100 or more: consider delivery at 35–36 weeks; 40–99: 36–37 weeks; under 40: by 38–39 weeks (local protocol; earlier for fetal compromise or deranged liver function)
AfterwardsItch and liver tests settle within 1–2 weeks; repeat liver tests at 6–8 weeks; recurrence about 60–90%; avoid oestrogen-containing contraception until normal

Rare, third trimester: sheets of sterile pustules in flexures and trunk, with fever, malaise, vomiting; low calcium and albumin cause tetany, seizures

Risks: maternal sepsis and collapse, placental insufficiency, stillbirth, and neonatal death

Treat: admit, correct calcium and fluids, oral prednisolone 30–60 mg daily, ciclosporin if needed, antibiotics for infection; deliver if refractory or fetal compromise

Differential: pustular drug eruption, bacterial infection, and generalised pustular psoriasis from steroid withdrawal

STEP 3 · OTHER SKIN PROBLEMS — and safe drug choices
🩹 PRE-EXISTING AND COMMON SKIN DISEASES
ConditionManagement in pregnancy
AcneTopical benzoyl peroxide, azelaic acid, erythromycin or clindamycin; avoid isotretinoin, oral tetracyclines, and topical retinoids
PsoriasisEmollients, topical steroids, narrowband UVB; ciclosporin or certolizumab for severe disease; avoid methotrexate, acitretin, and PUVA (psoralen with ultraviolet A); may improve in pregnancy, flares after
Atopic eczemaEmollients, topical steroids, sedating antihistamines at night; treat infection
ScabiesCommon in India; permethrin 5% cream over the whole body for 8–12 hours, repeat in 7 days; treat contacts; avoid lindane
Fungal infectionsTopical clotrimazole or terbinafine; avoid oral griseofulvin and high-dose fluconazole; vaginal candidiasis: clotrimazole pessary for 7 days
Genital wartsGrow faster in pregnancy; trichloroacetic acid or cryotherapy; avoid podophyllin and imiquimod; caesarean only if obstructing
Herpes zoster and varicellaAcyclovir or valacyclovir; see the TORCH sheet for exposure and delivery plans
UrticariaNon-sedating antihistamines (loratadine, cetirizine); look for a trigger; short oral steroid if severe
LeprosyMultidrug therapy is considered safe and should continue; reactions and nerve damage may appear in pregnancy and after delivery — refer early
Lupus and syphilis rashesLupus: risk of neonatal lupus and heart block; syphilis: palm and sole rash, test and treat (see the dedicated sheet)
GroupAdvice
Generally safeEmollients, mild to moderate topical steroids, sunscreen, benzoyl peroxide, azelaic acid, permethrin, topical clotrimazole, chlorphenamine, loratadine, cetirizine, oral prednisolone, narrowband UVB
Use with carePotent or very potent topical steroids (small areas, shortest time; large amounts may lower birth weight), ciclosporin, azathioprine, dapsone (watch for haemolysis), oral fluconazole
AvoidIsotretinoin, acitretin, topical tretinoin; methotrexate; oral tetracyclines (doxycycline); thalidomide; finasteride and dutasteride; oral minoxidil; lindane; podophyllin; PUVA
BreastfeedingEmollients, mild steroids, and permethrin are fine; do not apply creams to the nipple before feeds; avoid methotrexate and retinoids
⚠️ COMMON PITFALLS

Treating itch in late pregnancy with antihistamines alone without bile acids and liver tests

Calling a blistering rash 'PUPPP' without checking the navel and doing a biopsy — pemphigoid gestationis carries fetal risk

Normal liver tests on one occasion do not exclude ICP — repeat if the itch persists

Prescribing isotretinoin, tetracyclines, or methotrexate to a woman who may be pregnant

Using potent steroids on large areas for long periods, or calling scabies 'eczema' and missing the household source

Forgetting the postpartum period: PG flares, ICP recurrence advice, and telogen effluvium

Memory Aid

ITCHING

Seven rules for skin disease in pregnancy.
I
Itch without a rash — cholestasis until proved otherwise: bile acids and liver tests
T
Timing and site of onset — navel means pemphigoid; stretch marks mean PEP
C
Care with drugs — emollients, mild steroids, and safe antihistamines first
H
Hospital for pustular psoriasis and severe pemphigoid
I
Insist on fetal surveillance in ICP, pemphigoid, and pustular psoriasis
N
No isotretinoin, acitretin, methotrexate, tetracyclines
G
Give a postpartum plan — delivery timing, flares, and recurrence
Remember: rash or no rash, test the itch, protect the baby, and choose safe drugs.

Reproductive Morbidity and Maternal Mortality

Swaraj Hospital logo
SWARAJ HOSPITAL & RESEARCH INSTITUTE
BOLANGIR, ODISHA  •  OBSTETRICS & GYNAECOLOGY CLINICAL PATHWAY SERIES
Clinician Reference Infographic

Reproductive Morbidity and Maternal Mortality

Maternal deaths and reproductive illness are largely preventable. This guide covers definitions and burden, causes and prevention, reproductive morbidity, near misses, health-system delays and programmes, and death review, using the MOTHER approach.

Maternal death is the tip of the iceberg: for each woman who dies, many more survive severe illness, injury, or lasting disability (reproductive morbidity)

About 260,000 women died worldwide in 2023 (maternal mortality ratio 197 per 100,000 live births), about 40% lower than in 2000; around 87% of these deaths were in sub-Saharan Africa and southern Asia (World Health Organization, WHO)

India's ratio was 88 per 100,000 live births in 2021–23 (Sample Registration System, SRS) — far below 1998 (398) but still above the Sustainable Development Goal target of under 70 by 2030

Most deaths are preventable: severe bleeding, hypertensive disorders, infection, obstructed labour, and unsafe abortion respond to well-known, low-cost care delivered on time

Reviewing every death and near miss turns tragedy into local action — the core of Maternal Death Surveillance and Response (MDSR)

Every maternal death has a cause and a delay behind it — find both, fix the system, and do not blame the individual
🚨 DANGER SIGNS — REFER IMMEDIATELY
Vaginal bleeding in pregnancy, heavy bleeding after delivery, or a bleeding woman who is pale, faint, or drowsy
Severe headache, blurred vision, upper abdominal pain, convulsions, or blood pressure 160/110 mmHg or more
Fever, foul-smelling discharge, or severe lower abdominal pain after delivery, miscarriage, or abortion
Difficulty breathing, chest pain, calf swelling, or severe anaemia (haemoglobin below 7 g/dL)
Labour over 12 hours, absent fetal movements, or leaking fluid before labour
🗺️ THE PATHWAY AT A GLANCE
1 · PreventContraception, safe abortion, folic acid, anaemia correction, vaccination
2 · Detect earlyAntenatal contacts, risk screening, blood pressure, haemoglobin, danger-sign teaching
3 · PlanBirth preparedness, a delivery site matched to risk, transport, blood
4 · Deliver safelySkilled attendance, partograph, active management of the third stage, respectful care
5 · RespondEmergency obstetric care, high-dependency care, referral without delay
6 · ReviewNotify, review, act: deaths and near misses feed back into care
STEP 1 · DEFINITIONS AND BURDEN — know what is being counted
TermMeaning
Maternal deathDeath of a woman while pregnant or within 42 days of the end of pregnancy, from any cause related to or made worse by the pregnancy or its management, but not from accidental or incidental causes (WHO, International Classification of Diseases)
Late maternal deathDeath from direct or indirect obstetric causes more than 42 days but less than 1 year after the end of pregnancy
Pregnancy-related deathDeath during pregnancy or within 42 days whatever the cause
Direct and indirect causesDirect: obstetric complications, interventions, omissions, or incorrect treatment; indirect: pre-existing or new disease made worse by pregnancy (heart disease, anaemia, malaria, HIV, tuberculosis, hepatitis)
Maternal mortality ratio (MMR)Maternal deaths per 100,000 live births; maternal mortality rate uses women of reproductive age as the denominator; lifetime risk combines fertility and the ratio
Severe maternal morbidityLife-threatening complications (for example haemorrhage needing transfusion, eclampsia, sepsis, hysterectomy, ventilation) in a woman who survives
Maternal near missA woman who nearly died but survived a complication in pregnancy, childbirth, or within 42 days (WHO criteria: clinical signs, laboratory markers, or life-saving management)
Reproductive morbidityAny illness or disability of the reproductive system or from reproduction, obstetric or gynaecological, physical, sexual, or mental
🌍 HOW BIG IS THE PROBLEM?
MeasureFigure
Global (2023, WHO)About 260,000 maternal deaths; ratio 197 per 100,000 live births; about 40% decline since 2000; about 87% of deaths in sub-Saharan Africa and southern Asia; Sustainable Development Goal 3.1: under 70 by 2030
India (Sample Registration System)88 per 100,000 live births in 2021–23 (about 22,500 deaths in a year); 398 in 1998; states differ widely — check the latest bulletin for Odisha and for your district
Leading global causesSevere bleeding (mostly after delivery), infection (usually after delivery), hypertensive disorders (pre-eclampsia and eclampsia), delivery complications, and unsafe abortion account for about 75% of deaths; the rest are mainly indirect causes
Approximate shares (from memory)Haemorrhage about 27%, hypertensive disorders about 14%, sepsis about 11%, abortion about 8%, embolism about 3%, indirect causes about 28% (WHO systematic analysis)
India — unsafe abortionAbout 5% of maternal deaths in the Million Death Study (2007–2014); haemorrhage was the leading cause nationally
When deaths occurMost during labour, delivery, and the first 24 hours after birth, and many in the first week — so care must not stop at delivery
STEP 2 · CAUSES AND PREVENTION — target the main killers
CausePrevention and early action
Obstetric haemorrhageTreat anaemia; oxytocin 10 IU intramuscularly after birth and active management of the third stage; tranexamic acid 1 g intravenously within 3 hours of birth for bleeding; uterine massage, balloon tamponade, compression sutures; blood and a protocol ready (see the haemorrhage sheet)
Hypertensive disordersCheck blood pressure and urine at every visit; low-dose aspirin (about 75–150 mg nightly from 12–16 weeks) for women at high risk; calcium supplement where dietary intake is low; magnesium sulfate for severe pre-eclampsia and eclampsia; treat severe hypertension quickly; deliver at the right time
SepsisClean delivery and hand hygiene; antibiotics for prolonged rupture of membranes and for caesarean; recognise early (fever, tachycardia, foul discharge); sepsis bundle within the first hour
Obstructed labour and ruptured uterusPlot the partograph; act at the alert and action lines; refer early; caesarean in a facility with a trained team
Unsafe abortionContraception, comprehensive abortion care within the law, and post-abortion care; treat incomplete abortion and septic abortion urgently
EmbolismPrevent venous thrombosis (mobilise, assess risk, give prophylaxis); consider amniotic fluid embolism in sudden collapse
Anaesthesia and surgical complicationsSkilled anaesthesia, airway equipment, safe surgical checklist, postoperative monitoring
🫀 INDIRECT CAUSES AND UNDERLYING FACTORS
FactorWhat to do
AnaemiaScreen early and repeat; iron and folic acid (India: 100 mg elemental iron and 500 µg folic acid daily for at least 180 days from the second trimester; WHO: 30–60 mg iron and 400 µg folic acid daily); treat severe anaemia in a facility
Heart diseasePre-pregnancy counselling; shared antenatal and delivery planning; deliver in a centre with a cardiology team
InfectionsMalaria, HIV, tuberculosis, hepatitis E, influenza, and COVID-19: screening, vaccination, treatment, and prevention (see the infection sheets)
Mental healthScreen for depression and anxiety in pregnancy and after birth; suicide is a leading cause of late maternal death in many countries
Social determinantsAdolescent pregnancy, poverty, low education, distance, domestic violence, and discrimination — address them with community and family support
Family planningBirth spacing of at least 2 years and access to contraception reduce risk and unsafe abortion
STEP 3 · REPRODUCTIVE MORBIDITY — the burden beyond death
GroupExamples
ObstetricAnaemia, severe maternal morbidity, hypertensive disease, postpartum haemorrhage, puerperal sepsis, perineal tears, obstetric fistula (an estimated 50,000 to 100,000 new cases each year worldwide), third- and fourth-degree tears, incontinence
GynaecologicalGenital prolapse, menstrual disorders, chronic pelvic pain, fibroids, endometriosis, cervical and breast cancer, and infertility
InfectionsReproductive tract and sexually transmitted infections, pelvic inflammatory disease, HIV, hepatitis B — with long-term effects such as infertility and ectopic pregnancy
Abortion and contraception-relatedUnintended pregnancy, unsafe abortion complications, contraceptive failure or side effects
Sexual and mental healthPostpartum depression and anxiety, post-traumatic stress after traumatic birth, sexual dysfunction, fear of childbirth
ViolenceIntimate-partner violence, sexual violence, and harmful practices cause injury, miscarriage, and chronic illness
Reproductive morbidity is often silent and unreported: ask about incontinence, pain, discharge, mood, and violence at antenatal, postnatal, and gynaecology visits — screen and treat, not just record
🔎 SEVERE MORBIDITY AND NEAR MISS
TopicDetails
WHO near-miss criteria (examples)Clinical: shock, cardiac arrest, convulsions, loss of consciousness, severe respiratory distress, cyanosis, jaundice with pre-eclampsia, stroke; laboratory: severe acidosis, hypoxaemia, acute renal failure markers, severe thrombocytopenia; management: hysterectomy, transfusion of 5 or more units, intubation and ventilation over 60 minutes, dialysis, cardiopulmonary resuscitation, vasoactive drugs
Why review near misses?They are far commoner than deaths, the woman can tell her story, and they reveal the same system weaknesses
Useful indicatorsMaternal near-miss ratio (near misses per 1,000 live births); mortality index = maternal deaths ÷ (deaths + near misses), showing the quality of care
ScaleFor every maternal death, many women suffer severe morbidity or lasting disability (WHO estimates about 20 to 30, in some settings more)
STEP 4 · THE HEALTH SYSTEM — delays, emergency care and programmes
DelayCauses and remedies
Delay 1 — in deciding to seek careNot recognising danger signs, family decision-makers, cost fears, distrust → community education, birth preparedness, danger-sign teaching, empowerment of the woman
Delay 2 — in reaching a facilityDistance, roads, no transport, no money → ambulance (108 or 102), community transport funds, birth waiting homes, early referral
Delay 3 — in receiving adequate careNo staff, drugs, blood, or theatre; poor skills; delay in decision; disrespect → trained teams, emergency obstetric care, blood storage, drill and protocols, stabilise and refer
Emergency obstetric careBasic: parenteral antibiotics, uterotonics, anticonvulsants, manual removal of placenta, removal of retained products, assisted vaginal birth, newborn resuscitation; comprehensive: these plus caesarean section and blood transfusion
Respectful maternity careNo abuse, privacy, consent, birth companion, and clear communication — women avoid facilities that disrespect them
🇮🇳 INDIAN PROGRAMMES (FROM MEMORY)
ProgrammePurpose
Janani Suraksha Yojana and Janani Shishu Suraksha KaryakramPromote institutional delivery; free delivery, drugs, diagnostics, diet, blood, and transport for mothers and sick newborns
Pradhan Mantri Surakshit Matritva AbhiyanFree, assured antenatal check by a specialist on the 9th of every month; identifies and follows up high-risk pregnancies
LaQshyaQuality improvement in labour rooms and maternity operation theatres (reduce haemorrhage, hypertension, sepsis, and avoid unnecessary caesareans)
Surakshit Matritva Aashwasan (SUMAN)Zero denial of assured, respectful, free care to every woman and newborn
Maternal Death Surveillance and Response (2017)Notify every maternal death, review at facility and community level, act on findings
Obstetric high-dependency and intensive care unitsDedicated critical care for the sickest women (see the Obstetric ICU sheet)
Anaemia Mukt BharatPrevent and treat anaemia with iron and folic acid, deworming, testing, and diet
STEP 5 · REVIEW AND AUDIT — learn from every death
StepWhat happens
1 · Identify and notifyEvery maternal death is reported within 24 hours to the district health authority (timelines from memory)
2 · Review at the facilityFacility-based maternal death review: case summary, timeline, root causes, by the treating team and a facilitator
3 · Community reviewVerbal autopsy and a home visit to learn about delays and social factors
4 · District and State reviewThe committee classifies the cause, finds avoidable factors, and assigns actions with owners and dates
5 · Act and follow upTraining, protocols, drugs and blood supply, transport, referral systems; check that actions were completed
Classification (WHO ICD-MM)Abortive outcome; hypertensive disorders; obstetric haemorrhage; pregnancy-related infection; other obstetric complications; complications of management; non-obstetric complications; unknown; coincidental
Reviews are confidential and blame-free: the aim is to find what in the system failed, not who to punish — staff must feel safe to tell the truth
🛠️ HOW TO RUN A GOOD REVIEW

Use a timeline: arrival, assessment, decisions, treatments, and escalation — with exact times

Ask 'why' repeatedly until you reach a root cause (no blood in the unit, no senior called, no protocol)

Judge avoidability across patient, community, provider, and system factors

Write actions that are specific, owned, dated, and measurable; feed back to the whole team and the community

Review near misses and good outcomes too — learn what went right

Late recognition and late escalation: a worsening woman is not called to a senior in time

Referral without stabilisation (no magnesium sulfate, no oxytocin, no IV access, no escort, no call ahead)

Blood or drugs not available, or anaemia left untreated before delivery

Under-reporting and misclassification of deaths (particularly after abortion and at home)

Blaming individuals instead of fixing systems

Ignoring the postpartum period — including mental health and family planning

Memory Aid

MOTHER

Six actions to save mothers and prevent morbidity.
M
Measure and review — notify every death, review every near miss, act on findings
O
Obstetric emergencies — treat bleeding, high blood pressure, and sepsis fast
T
Timely referral and transport — beat the three delays; stabilise before moving
H
Health before pregnancy — contraception, anaemia, vaccines, safe abortion access
E
Educate and screen — danger signs, risk assessment, birth preparedness
R
Respectful, skilled care — at birth and in the first week after
Remember: prevent, detect early, respond fast, and learn from every death.

Wednesday, October 21, 2026

Biomedical Waste Management

Swaraj Hospital logo
SWARAJ HOSPITAL & RESEARCH INSTITUTE
BOLANGIR, ODISHA  •  OBSTETRICS & GYNAECOLOGY CLINICAL PATHWAY SERIES
Clinician Reference Infographic

Biomedical Waste Management

Safe disposal of biomedical waste protects patients, staff, waste handlers, and the environment. This guide covers the Indian rules, the colour code, obstetric and gynaecological waste, safe handling, needle-stick response, and records, using the SORTING approach.

Biomedical waste is any waste produced in diagnosing, treating, or immunising humans or animals, or in related research; in India the Bio-Medical Waste Management Rules, 2016 (Ministry of Environment, Forest and Climate Change, notified 28 March 2016, amended since) govern it

The rules apply to everyone who generates, collects, stores, transports, treats, or disposes of it — including vaccination, blood donation, and surgical camps, not only hospitals

Most health-care waste is harmless (about 85% is general waste), but about 15% is infectious, toxic, or otherwise hazardous (World Health Organization) — mixing it all turns everything into expensive hazardous waste

Four colour-coded categories: yellow, red, white (translucent), and blue — segregate at the point of generation

Untreated waste must not be stored beyond 48 hours; staff must be trained and immunised; bar-coded bags go to an authorised common treatment facility; records are kept for 5 years

Segregation at the bedside is the whole system — if the wrong bin is used, no later step can fix it safely
🚨 NEVER
Recap, bend, break, or hand over a used needle — drop it straight into the white puncture-proof container
Mix sharps, plastics, glass, and soft waste or put infectious waste into the general (black) bag
Overfill a bag or container (seal at about three-quarters full) or reach into a bin or compress waste by hand
Keep untreated waste more than 48 hours, burn it in the open, or dump it in a landfill or drain
After a needle-stick or splash: do not delay — wash, report, and start post-exposure prophylaxis within hours
🗺️ THE WASTE PATHWAY AT A GLANCE
1 · SegregateAt the point of generation, into the right coloured bin
2 · CollectClosed trolleys, sealed bags, labelled, bar-coded
3 · StoreSecure, ventilated, signed store; no more than 48 hours
4 · TransportAuthorised vehicle of the common treatment facility
5 · Treat and disposeIncineration, autoclave, shredding, recycling, or approved burial
6 · Record and reportDaily register, accident report, annual report by 30 June
STEP 1 · THE RULES — what the law requires
TopicDetails
Who is coveredHospitals, nursing homes, clinics, laboratories, blood banks, camps, research and veterinary institutions, and anyone who handles the waste; excluded: radioactive waste, municipal solid waste, lead-acid batteries, e-waste, and hazardous microorganisms (other rules apply)
The occupier (hospital head or owner)Responsible for all duties: segregate, store, hand over to the common facility, train staff, immunise staff, and keep records
AuthorisationFrom the State Pollution Control Board (in Odisha, the Odisha State Pollution Control Board); one-time for non-bedded facilities; for bedded facilities, validity is linked to the consent order
Common treatment facilityNo on-site treatment if a common bio-medical waste treatment facility exists within 75 km; the operator collects waste on time, treats it, reports accidents, and helps with training
Storage limitNo untreated waste kept beyond 48 hours; if unavoidable, inform the Pollution Control Board with reasons
Pre-treatment of laboratory wasteDisinfect or sterilise laboratory and microbiological waste on site, by WHO or National AIDS Control Organisation methods, before it leaves the premises
Bar codeBags and containers sent out carry bar codes; common facilities track vehicles with GPS
PlasticsChlorinated plastic bags, gloves, and blood bags are phased out (they release dioxins and furans when burned); the 2018 amendment adjusted the deadlines
Annual reportOccupier to the prescribed authority by 30 June each year; the authority to the Central Pollution Control Board by 31 July; published on websites
Records and accidentsKeep records of generation, storage, transport, treatment, and disposal for 5 years; report major accidents at once and submit a report within 24 hours
PenaltiesUnder the Environment (Protection) Act, 1986 (penalties and compensation have been revised, so check the current provision) (from memory)
STEP 2 · THE COLOUR CODE — four categories, four containers
🎨 SEGREGATION, CONTAINERS AND TREATMENT
ColourWhat goes inContainer and treatment
🟡 YellowHuman anatomical waste (placenta, tissues, organs, fetus); soiled waste (dressings, swabs, pads, items contaminated with blood or body fluids); expired and discarded medicines and cytotoxic drugs; chemical waste; contaminated linen and bedding; laboratory and microbiology waste, blood bags (after on-site pre-treatment)Non-chlorinated yellow plastic bag (chemical liquids: separate collection to effluent treatment); incineration or plasma pyrolysis at the common facility; deep burial only in remote areas without a facility and with approval; expired medicines: return to the manufacturer or incinerate; soiled waste may be autoclaved and shredded where incineration is unavailable
🔴 RedContaminated recyclable plastics: tubing, IV sets, catheters, urine bags, suction tubing, bottles, syringes without needles, and glovesNon-chlorinated red plastic bag or container; autoclave, microwave, or hydroclave, then shred or mutilate; sent to authorised recyclers; never landfilled or incinerated
⚪ White (translucent)Sharps: needles, syringes with fixed needles, scalpel and surgical blades, suture needles, and any contaminated sharp metal objectPuncture-proof, leak-proof, tamper-proof container; autoclave or dry-heat sterilise, then shred, mutilate, or encapsulate; sent to authorised recyclers or foundries
🔵 BlueGlassware: broken or discarded contaminated glass, vials, and ampoules (except those contaminated with cytotoxic drugs); metallic body implantsCardboard box with blue marking; disinfect (wash with detergent, then sodium hypochlorite soak) or autoclave, then recycle
General (non-infectious) waste — paper, packaging, kitchen waste, and clean items — goes to the municipal stream in a separate black or other general bag; it must not enter the coloured bins (colour of general bins varies locally)
STEP 3 · OBSTETRICS AND GYNAECOLOGY — where the waste arises
ItemBin and notes
Placenta, membranes, products of conception, fetus, tissue from surgeryYellow (human anatomical waste); do not hand them over to families (follow the facility policy and local permission if a family requests it)
Blood-soaked swabs, mops, pads, drapes, and lochia padsYellow (soiled waste)
Used gloves, IV sets, catheters, urine bags, suction tubing, and cord-blood or amnio setsRed
Needles, blades, suture needles, scalpel handles with blades, and cannula styletsWhite; use a needle destroyer or hub cutter where provided
Empty oxytocin, methylergometrine, and magnesium sulfate ampoules or vials; broken glassBlue
Expired or unused drugsYellow (return to the manufacturer or common facility); cytotoxic drugs such as methotrexate in labelled cytotoxic yellow containers
Blood and body-fluid specimens, blood bags, and culture platesYellow, after on-site disinfection or sterilisation
Amniotic fluid, blood in suction bottles, and washingsDisinfect with sodium hypochlorite before drain disposal (per local sewage rules), or follow the facility's liquid waste protocol
Contaminated linen and gownsDisinfect and launder or treat as yellow waste if heavily soiled and disposable
Mercury thermometers and blood pressure instrumentsHazardous mercury: do not use bins; use a mercury spill kit and a mercury-free alternative (from memory)
Disposable speculums, scissors, and instrumentsReusable ones: decontaminate and sterilise; disposable plastic parts: red; metal blades: white
STEP 4 · SAFE HANDLING — protect staff and patients
🧤 HANDLING, STORAGE AND TRANSPORT
StepDetails
At the bedside and in the labour roomPlace the correct bins within reach, with the colour and a poster of what goes in; segregate immediately after the procedure; do not carry waste across the ward
Bags and sharps boxesUse non-chlorinated plastic bags; fill no more than about three-quarters; seal with a tie or lock; do not re-open; close and replace sharps containers when three-quarters full; label with date, ward, and bar code
Personal protective equipmentGloves, apron, mask, eye protection, and closed shoes for waste handlers; hand hygiene after removing gloves
Internal transportCovered, wheeled trolleys on fixed routes and at fixed times, kept away from patients, food, and clean supplies; clean and disinfect them daily
Storage roomWithin the premises, secure, ventilated, shaded, with a floor drain and a biohazard symbol; locked and accessible only to authorised staff; untreated waste out within 48 hours
SpillsCover with absorbent material, apply disinfectant (about 1% sodium hypochlorite, 10,000 ppm, for blood), wait about 10 minutes, then clean up wearing gloves; discard the cleaning materials as yellow waste (from memory)
Training and immunisationTrain all staff and cleaners at joining and every year; immunise everyone who handles waste against hepatitis B and tetanus (rules require both)
STEP 5 · INJURY AND EXPOSURE — needle-stick and splash
StepWhat to do
1 · Wash at onceSkin: wash with soap and running water, do not squeeze or scrub; eyes: irrigate with water or saline; mouth: rinse with water
2 · Report and assessInform the infection control officer or designated doctor immediately; record the source, type of exposure, and depth; fill the accident or exposure register
3 · TestSource patient (with consent) and the exposed worker: HIV, hepatitis B surface antigen, and hepatitis C antibody
4 · ProphylaxisHIV post-exposure prophylaxis as early as possible (ideally within 2 hours and not later than 72 hours) for a 28-day course per the National AIDS Control Organisation protocol; hepatitis B vaccine, plus immunoglobulin if non-immune, ideally within 24 hours; tetanus booster if needed (from memory)
5 · Follow upRepeat tests at 6 weeks, 3 months, and 6 months (per protocol); counsel; safe sex advice during follow-up; review how it happened and fix it
STEP 6 · RECORDS AND COMPLIANCE — show that it is done
🗂️ ACCOUNTABILITY
ItemDetails
Daily registerQuantity of waste by colour category, handed to the common facility with date and signature; keep for 5 years
Committee and nodal officerA bio-medical waste management committee (meets regularly) and a named officer to monitor, train, and report incidents
Annual reportBy 30 June each year, covering waste handled, training, immunisation, accidents, and treatment
Accident reportingReport major accidents immediately and submit a report within 24 hours
Audit and quality schemesRegular audits of segregation and storage; biomedical waste is part of the national Kayakalp and quality assessment checklists (from memory)
Reduce and reuseBuy less single-use plastic where safe, replace mercury devices, send recyclables for authorised recycling

Throwing everything into one bag or putting sharps in soft bags

Overfilled sharps containers and needles recapped or left on trays

Storage rooms that are open, dirty, or hold waste beyond 48 hours

Staff not immunised or not trained, especially cleaners and new nurses

Delayed reporting after a needle-stick

No daily register or annual report, or non-chlorinated bags not used

Giving the placenta away or putting it in the general bin

Memory Aid

SORTING

Seven habits for safe biomedical waste management.
S
Segregate at the source — right bin, right time, no mixing
O
One colour, one rule — yellow soft and anatomical, red plastics, white sharps, blue glass
R
Reduce and recycle — non-chlorinated bags, mercury-free devices, authorised recycling
T
Time limit — treated or collected within 48 hours; bar-coded bags to the common facility
I
Immunise and protect staff — hepatitis B, tetanus, gloves, and training
N
Needle-stick plan — wash, report, test, prophylaxis within hours
G
Give proof — daily register, accident report, annual report by 30 June
Remember: segregate, store safely, hand over in time, protect staff, and keep records.

Tuesday, October 20, 2026

Obstetric ICU

Swaraj Hospital logo
SWARAJ HOSPITAL & RESEARCH INSTITUTE
BOLANGIR, ODISHA  •  OBSTETRICS & GYNAECOLOGY CLINICAL PATHWAY SERIES
Clinician Reference Infographic

Obstetric ICU — Care of the Critically Ill Mother

The obstetric ICU and HDU bring skilled, early care to women with life-threatening complications. This guide follows the Government of India (MoHFW) guidelines on unit design, staffing, admission, monitoring, protocols, discharge, and referral, with organ support in pregnancy and the CRITICAL approach.

An obstetric high-dependency unit (HDU) and intensive care unit (ICU) care for women with life-threatening complications of pregnancy, childbirth, or the puerperium — "when things go wrong in obstetrics, they go wrong fast"

HDU = step-up and step-down care for single-organ or no-organ support; ICU = multi-organ failure or advanced support (ventilation, inotropes, dialysis), led by an intensivist

The main reasons for admission are haemorrhage, hypertensive disorders (eclampsia, HELLP), sepsis, heart disease, respiratory failure, and acute kidney or liver failure

Pregnancy changes everything: airway, oxygenation, blood pressure targets, drug choice, and the fetus — treat the mother first, because a stable mother is the best treatment for the baby

Early transfer saves lives: do not wait for the woman to deteriorate; the right level of care, at the right time, by trained staff
🚨 MOVE FROM HDU TO ICU IF (MoHFW)
Pulmonary oedema, acute respiratory distress syndrome (ARDS), or oxygen need that rises despite treatment
Systemic inflammatory response (SIRS), septic shock, or poor cardiac output despite fluids
Disseminated intravascular coagulation (DIC) or multi-organ failure
Need for ventilation, inotropes, or dialysis, or a falling level of consciousness
🗺️ THE PATHWAY AT A GLANCE
1 · RecogniseEarly-warning score triggers; senior review without delay
2 · TriageWard, HDU, or ICU; obstetrician and intensivist decide together
3 · StabiliseAirway, oxygen, circulation, left tilt, treat the cause
4 · SupportOrgan support, fetal plan, thromboprophylaxis, nutrition
5 · MonitorHourly observations in the acute phase; protocols and records
6 · Step downDischarge criteria, follow-up, counselling, case review
STEP 1 · THE UNIT — design, staff, and equipment (MoHFW guidelines)
TopicDetails (Ministry of Health and Family Welfare)
HDU versus ICUHDU: between the labour ward and the ICU; single-organ or no-organ support; usually not for ventilated or multi-organ failure patients; ICU: multi-organ failure or advanced support, led by an intensivist
Number of bedsUp to 250 deliveries a month: 4 beds; 250–500: 8 beds; over 500: increase in proportion; one isolation room (about 150 sq ft) for infectious cases
Space and locationAbout 120–130 sq ft per HDU bed and 130–150 per ICU bed; next to the labour room and theatre, near the ICU, laboratory, radiology, and blood bank; one entry, emergency exits
StaffNurse-to-patient ratio 1:2 in HDU and 1:1 in ICU; HDU headed by a full-time obstetrician; 8-bed HDU: 4 nurses and 2 emergency obstetric care medical officers per shift; 4-bed ICU: 4 nurses and an intensivist; anaesthetist present 24 hours; on-call physician, paediatrician, surgeon, radiologist
EquipmentBedside monitors (oxygen saturation, blood pressure, ECG, respiration, temperature), infusion and syringe pumps, ultrasound with colour Doppler, cardiotocography, defibrillator and crash cart, transport and non-invasive ventilators, arterial blood gas machine, blood warmer, eclampsia box, Bakri balloon, intubation equipment
Per bedAt least 2 oxygen, 1 air, and 2 suction outlets and about 10 power points; backup power, fire safety, biomedical waste management, ambulance with newborn transport support
TrainingOrientation for nurses and medical officers; 3 months of ICU posting for medical officers; emergency drills every 3 months; emergency trolley checked daily; everyone trained in CPR
STEP 2 · ADMISSION AND TRIAGE — who needs which level of care
🚪 WHO SHOULD BE ADMITTED
LevelTypical conditions
HDU (MoHFW list)Severe anaemia, haemorrhage, pre-eclampsia, eclampsia, HELLP syndrome (haemolysis, elevated liver enzymes, low platelets), sepsis, DIC, placental problems; cardiac disease, thyroid disorders, diabetic complications, dengue, malaria, asthma; surgical or trauma cases; or clinical judgement
ICU (physiological thresholds)Very low or very high blood pressure, low Glasgow coma score, abnormal electrolytes or pH, low oxygen despite oxygen therapy, need for ventilation or inotropes, DIC, ARDS, multi-organ failure (use the national tables for exact values)
Common triggers (general)Respiratory rate over 30 or under 10, saturation under 90% on oxygen, systolic pressure under 90, urine under 0.5 mL/kg/hour for 2 hours, lactate over 4, seizures or coma, platelets under 50,000 with bleeding
Who decidesObstetrician with the intensivist or anaesthetist; ICU referral only after ICU admission is assured; a mother's baby moves with her if already delivered
STEP 3 · ORGAN SUPPORT IN PREGNANCY — what changes at the bedside
SystemAdvice
AirwayDifficult and failed intubation are commoner (oedema, large breasts, obesity); aspiration risk; pre-oxygenate well (desaturates quickly); senior operator, video laryngoscope, smaller tube
BreathingTarget saturation of 95% or more and PaO₂ of 70 or more; lung-protective ventilation (6 mL/kg ideal body weight); avoid high PaCO₂ (above about 45–50) because it acidifies the fetus; normal pregnant PaCO₂ is 28–32 (see the ABG sheet)
CirculationLeft lateral tilt (about 15°) if over 20 weeks; mean arterial pressure of 65 or more; noradrenaline first for septic shock; restrict fluids in pre-eclampsia (pulmonary oedema risk)
KidneyHourly urine output; avoid nephrotoxic drugs (NSAIDs, aminoglycosides); dialysis for refractory acidosis, hyperkalaemia, overload, or uraemia
BrainSeizures: magnesium sulfate for eclampsia (see the neurology sheet); exclude other causes (stroke, cerebral venous thrombosis, hypoglycaemia)
BloodMassive haemorrhage protocol, tranexamic acid 1 g, correct DIC (fibrinogen above 2 g/L, platelets above 50,000 if bleeding); Bakri balloon for atony
InfectionCultures and broad-spectrum antibiotics within the first hour; find and remove the source (retained products, abscess, hysterectomy)
Metabolic and nutritionAvoid hypoglycaemia; early enteral feeding; correct electrolytes; treat ketoacidosis with insulin infusion
ThromboprophylaxisLow molecular weight heparin (weight-based) and stockings unless bleeding or very low platelets
Analgesia and sedationAdequate pain relief; avoid over-sedation; check drug safety for breastfeeding
STEP 4 · CONDITION-SPECIFIC CARE — the commonest reasons for admission
🩺 KEY ICU ACTIONS BY CONDITION
ConditionKey actions
Severe pre-eclampsia, eclampsia, HELLPTreat severe hypertension within 30–60 minutes (labetalol, nifedipine, hydralazine); magnesium sulfate with monitoring of reflexes, respiration, and urine; restrict fluids; deliver after stabilisation; watch for pulmonary oedema, renal failure, liver haematoma
Obstetric haemorrhage and DICHaemostatic resuscitation (red cells, plasma, platelets, fibrinogen), tranexamic acid, surgical control, warm the patient, correct calcium
Sepsis and septic shockAntibiotics within an hour, fluids with caution, noradrenaline for a mean pressure under 65, source control; influenza in pregnancy: oseltamivir at once without waiting for a test
Heart diseasePeripartum cardiomyopathy and valve disease: echocardiography, diuretics, rate control, anticoagulation as indicated; avoid fluid overload
Amniotic fluid embolismSupportive care, manage the coagulopathy, consider extracorporeal support
ARDS and pneumoniaLung-protective ventilation, prone positioning is possible, treat the infection, extracorporeal support if refractory
Acute fatty liver and acute liver failureDeliver, glucose monitoring, correct coagulopathy, liver unit referral (see the liver sheet)
Diabetic ketoacidosisInsulin infusion, fluids, potassium; can occur at near-normal glucose in pregnancy (see the diabetes sheet)
STEP 5 · MONITORING, FETUS AND DISCHARGE — the whole picture
TopicDetails
Monitoring (MoHFW)Temperature, blood pressure, heart rate, respiratory rate, oxygen saturation, and urine output at least hourly in the acute phase; fluid and electrolyte balance; treat the cause
The fetusContinuous cardiotocography when viable; left lateral tilt about 15° and oxygen; corticosteroids if under 34 weeks; magnesium for neuroprotection before 32 weeks; deliver when it helps the mother (pre-eclampsia, chorioamnionitis, abruption, fatty liver) — not simply to improve a mother's lungs or heart
Protocols (MoHFW)Written SOPs for admission and discharge, resuscitation, major haemorrhage, pre-eclampsia and eclampsia, severe blood pressure disorders, diabetic ketoacidosis, sepsis, difficult intubation, anaesthesia and analgesia, post-dural puncture headache, thromboprophylaxis
Discharge from HDU (MoHFW)Stable circulation, no need for intensive monitoring, no continuous intravenous drugs or frequent blood tests, no active bleeding or oxygen need, walking; HDU stay is usually 24–72 hours
Records and referral (MoHFW)History, diagnosis, tests, operative notes, summary, dated and signed entries, consent and family counselling documented; referral slip, emergency drugs, escort with infusions, monitoring, secure airway
Family and follow-upDaily, honest communication; support for the woman's mental health (depression and post-traumatic stress are common); breastfeeding, contraception, and counselling for future pregnancy; near-miss review of every ICU admission (see the collapse sheet)
⚠️ COMMON PITFALLS

Late recognition and late transfer; treating on the ward what needs the HDU

Using non-pregnant targets (PaCO₂, blood pressure, oxygen) or forgetting left tilt

Fluid overload in pre-eclampsia, or too little fluid in haemorrhage and sepsis

Delivering a very sick mother for the baby's sake before she is stabilised

No thromboprophylaxis, no hourly chart, poor handover, or no record of consent

Forgetting the baby, the family, and the woman's mind after she leaves the unit

Memory Aid

CRITICAL

Eight rules for the critically ill mother.
C
Choose the right level — ward, HDU, or ICU; obstetrician and intensivist together
R
Recognise early — early-warning score and hourly observations
I
Intervene on the cause — bleeding, blood pressure, sepsis, heart, lungs
T
Tilt and oxygen — left lateral tilt, saturation 95% or more
I
Involve the team — obstetrician, intensivist, anaesthetist, neonatologist, nurse
C
Care for the fetus — monitor, steroids under 34 weeks, deliver when it helps her
A
Audit and record — protocols, signed notes, near-miss review
L
Look after family and follow-up — mental health, contraception, next pregnancy
Remember: recognise early, choose the right level, treat the cause, and care for the whole family.

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