
Reproductive Morbidity and Maternal Mortality
Maternal death is the tip of the iceberg: for each woman who dies, many more survive severe illness, injury, or lasting disability (reproductive morbidity)
About 260,000 women died worldwide in 2023 (maternal mortality ratio 197 per 100,000 live births), about 40% lower than in 2000; around 87% of these deaths were in sub-Saharan Africa and southern Asia (World Health Organization, WHO)
India's ratio was 88 per 100,000 live births in 2021–23 (Sample Registration System, SRS) — far below 1998 (398) but still above the Sustainable Development Goal target of under 70 by 2030
Most deaths are preventable: severe bleeding, hypertensive disorders, infection, obstructed labour, and unsafe abortion respond to well-known, low-cost care delivered on time
Reviewing every death and near miss turns tragedy into local action — the core of Maternal Death Surveillance and Response (MDSR)
| Term | Meaning |
|---|---|
| Maternal death | Death of a woman while pregnant or within 42 days of the end of pregnancy, from any cause related to or made worse by the pregnancy or its management, but not from accidental or incidental causes (WHO, International Classification of Diseases) |
| Late maternal death | Death from direct or indirect obstetric causes more than 42 days but less than 1 year after the end of pregnancy |
| Pregnancy-related death | Death during pregnancy or within 42 days whatever the cause |
| Direct and indirect causes | Direct: obstetric complications, interventions, omissions, or incorrect treatment; indirect: pre-existing or new disease made worse by pregnancy (heart disease, anaemia, malaria, HIV, tuberculosis, hepatitis) |
| Maternal mortality ratio (MMR) | Maternal deaths per 100,000 live births; maternal mortality rate uses women of reproductive age as the denominator; lifetime risk combines fertility and the ratio |
| Severe maternal morbidity | Life-threatening complications (for example haemorrhage needing transfusion, eclampsia, sepsis, hysterectomy, ventilation) in a woman who survives |
| Maternal near miss | A woman who nearly died but survived a complication in pregnancy, childbirth, or within 42 days (WHO criteria: clinical signs, laboratory markers, or life-saving management) |
| Reproductive morbidity | Any illness or disability of the reproductive system or from reproduction, obstetric or gynaecological, physical, sexual, or mental |
| Measure | Figure |
|---|---|
| Global (2023, WHO) | About 260,000 maternal deaths; ratio 197 per 100,000 live births; about 40% decline since 2000; about 87% of deaths in sub-Saharan Africa and southern Asia; Sustainable Development Goal 3.1: under 70 by 2030 |
| India (Sample Registration System) | 88 per 100,000 live births in 2021–23 (about 22,500 deaths in a year); 398 in 1998; states differ widely — check the latest bulletin for Odisha and for your district |
| Leading global causes | Severe bleeding (mostly after delivery), infection (usually after delivery), hypertensive disorders (pre-eclampsia and eclampsia), delivery complications, and unsafe abortion account for about 75% of deaths; the rest are mainly indirect causes |
| Approximate shares (from memory) | Haemorrhage about 27%, hypertensive disorders about 14%, sepsis about 11%, abortion about 8%, embolism about 3%, indirect causes about 28% (WHO systematic analysis) |
| India — unsafe abortion | About 5% of maternal deaths in the Million Death Study (2007–2014); haemorrhage was the leading cause nationally |
| When deaths occur | Most during labour, delivery, and the first 24 hours after birth, and many in the first week — so care must not stop at delivery |
| Cause | Prevention and early action |
|---|---|
| Obstetric haemorrhage | Treat anaemia; oxytocin 10 IU intramuscularly after birth and active management of the third stage; tranexamic acid 1 g intravenously within 3 hours of birth for bleeding; uterine massage, balloon tamponade, compression sutures; blood and a protocol ready (see the haemorrhage sheet) |
| Hypertensive disorders | Check blood pressure and urine at every visit; low-dose aspirin (about 75–150 mg nightly from 12–16 weeks) for women at high risk; calcium supplement where dietary intake is low; magnesium sulfate for severe pre-eclampsia and eclampsia; treat severe hypertension quickly; deliver at the right time |
| Sepsis | Clean delivery and hand hygiene; antibiotics for prolonged rupture of membranes and for caesarean; recognise early (fever, tachycardia, foul discharge); sepsis bundle within the first hour |
| Obstructed labour and ruptured uterus | Plot the partograph; act at the alert and action lines; refer early; caesarean in a facility with a trained team |
| Unsafe abortion | Contraception, comprehensive abortion care within the law, and post-abortion care; treat incomplete abortion and septic abortion urgently |
| Embolism | Prevent venous thrombosis (mobilise, assess risk, give prophylaxis); consider amniotic fluid embolism in sudden collapse |
| Anaesthesia and surgical complications | Skilled anaesthesia, airway equipment, safe surgical checklist, postoperative monitoring |
| Factor | What to do |
|---|---|
| Anaemia | Screen early and repeat; iron and folic acid (India: 100 mg elemental iron and 500 µg folic acid daily for at least 180 days from the second trimester; WHO: 30–60 mg iron and 400 µg folic acid daily); treat severe anaemia in a facility |
| Heart disease | Pre-pregnancy counselling; shared antenatal and delivery planning; deliver in a centre with a cardiology team |
| Infections | Malaria, HIV, tuberculosis, hepatitis E, influenza, and COVID-19: screening, vaccination, treatment, and prevention (see the infection sheets) |
| Mental health | Screen for depression and anxiety in pregnancy and after birth; suicide is a leading cause of late maternal death in many countries |
| Social determinants | Adolescent pregnancy, poverty, low education, distance, domestic violence, and discrimination — address them with community and family support |
| Family planning | Birth spacing of at least 2 years and access to contraception reduce risk and unsafe abortion |
| Group | Examples |
|---|---|
| Obstetric | Anaemia, severe maternal morbidity, hypertensive disease, postpartum haemorrhage, puerperal sepsis, perineal tears, obstetric fistula (an estimated 50,000 to 100,000 new cases each year worldwide), third- and fourth-degree tears, incontinence |
| Gynaecological | Genital prolapse, menstrual disorders, chronic pelvic pain, fibroids, endometriosis, cervical and breast cancer, and infertility |
| Infections | Reproductive tract and sexually transmitted infections, pelvic inflammatory disease, HIV, hepatitis B — with long-term effects such as infertility and ectopic pregnancy |
| Abortion and contraception-related | Unintended pregnancy, unsafe abortion complications, contraceptive failure or side effects |
| Sexual and mental health | Postpartum depression and anxiety, post-traumatic stress after traumatic birth, sexual dysfunction, fear of childbirth |
| Violence | Intimate-partner violence, sexual violence, and harmful practices cause injury, miscarriage, and chronic illness |
| Topic | Details |
|---|---|
| WHO near-miss criteria (examples) | Clinical: shock, cardiac arrest, convulsions, loss of consciousness, severe respiratory distress, cyanosis, jaundice with pre-eclampsia, stroke; laboratory: severe acidosis, hypoxaemia, acute renal failure markers, severe thrombocytopenia; management: hysterectomy, transfusion of 5 or more units, intubation and ventilation over 60 minutes, dialysis, cardiopulmonary resuscitation, vasoactive drugs |
| Why review near misses? | They are far commoner than deaths, the woman can tell her story, and they reveal the same system weaknesses |
| Useful indicators | Maternal near-miss ratio (near misses per 1,000 live births); mortality index = maternal deaths ÷ (deaths + near misses), showing the quality of care |
| Scale | For every maternal death, many women suffer severe morbidity or lasting disability (WHO estimates about 20 to 30, in some settings more) |
| Delay | Causes and remedies |
|---|---|
| Delay 1 — in deciding to seek care | Not recognising danger signs, family decision-makers, cost fears, distrust → community education, birth preparedness, danger-sign teaching, empowerment of the woman |
| Delay 2 — in reaching a facility | Distance, roads, no transport, no money → ambulance (108 or 102), community transport funds, birth waiting homes, early referral |
| Delay 3 — in receiving adequate care | No staff, drugs, blood, or theatre; poor skills; delay in decision; disrespect → trained teams, emergency obstetric care, blood storage, drill and protocols, stabilise and refer |
| Emergency obstetric care | Basic: parenteral antibiotics, uterotonics, anticonvulsants, manual removal of placenta, removal of retained products, assisted vaginal birth, newborn resuscitation; comprehensive: these plus caesarean section and blood transfusion |
| Respectful maternity care | No abuse, privacy, consent, birth companion, and clear communication — women avoid facilities that disrespect them |
| Programme | Purpose |
|---|---|
| Janani Suraksha Yojana and Janani Shishu Suraksha Karyakram | Promote institutional delivery; free delivery, drugs, diagnostics, diet, blood, and transport for mothers and sick newborns |
| Pradhan Mantri Surakshit Matritva Abhiyan | Free, assured antenatal check by a specialist on the 9th of every month; identifies and follows up high-risk pregnancies |
| LaQshya | Quality improvement in labour rooms and maternity operation theatres (reduce haemorrhage, hypertension, sepsis, and avoid unnecessary caesareans) |
| Surakshit Matritva Aashwasan (SUMAN) | Zero denial of assured, respectful, free care to every woman and newborn |
| Maternal Death Surveillance and Response (2017) | Notify every maternal death, review at facility and community level, act on findings |
| Obstetric high-dependency and intensive care units | Dedicated critical care for the sickest women (see the Obstetric ICU sheet) |
| Anaemia Mukt Bharat | Prevent and treat anaemia with iron and folic acid, deworming, testing, and diet |
| Step | What happens |
|---|---|
| 1 · Identify and notify | Every maternal death is reported within 24 hours to the district health authority (timelines from memory) |
| 2 · Review at the facility | Facility-based maternal death review: case summary, timeline, root causes, by the treating team and a facilitator |
| 3 · Community review | Verbal autopsy and a home visit to learn about delays and social factors |
| 4 · District and State review | The committee classifies the cause, finds avoidable factors, and assigns actions with owners and dates |
| 5 · Act and follow up | Training, protocols, drugs and blood supply, transport, referral systems; check that actions were completed |
| Classification (WHO ICD-MM) | Abortive outcome; hypertensive disorders; obstetric haemorrhage; pregnancy-related infection; other obstetric complications; complications of management; non-obstetric complications; unknown; coincidental |
Use a timeline: arrival, assessment, decisions, treatments, and escalation — with exact times
Ask 'why' repeatedly until you reach a root cause (no blood in the unit, no senior called, no protocol)
Judge avoidability across patient, community, provider, and system factors
Write actions that are specific, owned, dated, and measurable; feed back to the whole team and the community
Review near misses and good outcomes too — learn what went right
Late recognition and late escalation: a worsening woman is not called to a senior in time
Referral without stabilisation (no magnesium sulfate, no oxytocin, no IV access, no escort, no call ahead)
Blood or drugs not available, or anaemia left untreated before delivery
Under-reporting and misclassification of deaths (particularly after abortion and at home)
Blaming individuals instead of fixing systems
Ignoring the postpartum period — including mental health and family planning



