Wednesday, August 31, 2011

Does Exclusive Breastfeeding Prevent Eczema? It Appears Not

There is no clear evidence showing that exclusive breastfeeding for at least four months reduces the chances of a baby eventually developing eczema, researchers reported in the British Journal of Dermatology. The authors, from King's College London, say that in view of their findings, the UK's breastfeeding guidelines with regards to eczema should be reviewed.

This study was a joint collaboration between researchers from King's College London, the University of Ulm, Germany, and the University of Nottingham, England. They gathered data on 51,119 children aged 8 to 12 years from 21 nations.

The investigators collected data on breastfeeding, when the baby was weaned, and eczema. Parents had to fill in questionnaires. The children were given a skin examination for eczema, as well as a skin prick test to determine whether they had any allergies.

Previous studies had indicated that breastfeeding might protect from eczema. WHO (World Health Organization) and the UK Department of Health recommend six months of exclusive breastfeeding to reduce eczema risk.

However, in keeping with the findings in this present study, the researchers reviewed more recent articles and found no evidence showing that exclusive breastfeeding for four months or more reduced the risk of developing eczema.
original article

Newborn Death Rate Higher In USA Than 40 Other Countries !!!!

The USA is in 41st place worldwide regarding newborn mortality rate, a drop from 29th place in 1990. America's newborn death rate today is equal to that of Croatia, Qatar and the United Arab Emirates, according to a new report published in PLoS Medicine. The article is a collaboration between WHO (World Health Organization) and Save the Children, which covers all 193 WHO member nations over two decades. Don't believe Read the ORIGINAL ARTICLE .

Tuesday, August 23, 2011

Thin Children Have More Energy-Burning 'Brown Fat'

Thin Children Have More Energy-Burning 'Brown Fat'

THURSDAY, Aug. 18 (HealthDay News) -- Brown fat, also known as "good fat," burns more energy in active, thinner children and may help fight against obesity and diabetes, according to a new study.
Unlike white fat, which stores energy and appears to promote inflammation, brown fat actually burns energy.
These findings could help develop medications as well as drug-free ways to boost brown fat activity in overweight children, according to researchers from the Joslin Diabetes Center and Children's Hospital Boston.
Being able to evaluate brown fat's activity through non-invasive PET imaging "may possibly provide insights into the treatment of childhood obesity," the study's first author, Dr. Laura Drubach, of the Children's Hospital program in nuclear medicine and molecular imaging, said in a Joslin news release.
After conducting PET scans on 172 study participants ranging in age from 5 to 21 years, the researchers detected active brown fat in 44 percent of the children. They pointed out that boys and girls had roughly the same amount.
Children aged 13 to 15 years old had the highest levels of brown fat and brown fat activity. Those with the lowest body mass index (the thinnest teens) showed the most energy-burning activity in their "good fat."
The study authors said the inverse relationship between body mass index and levels of brown fat activity -- and the increase in brown fat activity from childhood into adolescence -- suggests "good fat" may play a significant role in children's metabolism, energy balance and weight regulation.
And contrary to previous studies that showed brown fat in adults was more active in cold weather, the researchers found outdoor temperatures had no effect on brown fat in children.
The researchers concluded that their findings could help develop ways to combat obesity by boosting brown fat activity in children, such as lowering indoor temperatures in homes where obese children live. They noted, however, that more research is needed to explain whether thin children have more brown fat because they are thin or whether having more brown fat makes them thin.
"That's the billion dollar question," concluded the study's senior author, Dr. Aaron Cypess, assistant investigator and staff physician at Joslin. "But we do know that brown fat is a core component of pediatric and likely adult metabolism," he said in the news release.
The study was released online Aug. 12 in advance of publication in an upcoming print issue of The Journal of Pediatrics.
SOURCE: Joslin Diabetes Center, news release, Aug. 11, 2011
http://www.nlm.nih.gov/medlineplus/news/fullstory_115536.html

Saturday, August 20, 2011

Serial Killer' Immune Cells Put Cancer in Remission

The patient was dying of leukemia. One hundred seventy out of every 200 cells in his bone marrow had a cancer-causing mutation, and his lymph nodes were swelling, a sign the cancer was getting worse. He'd already been on multiple courses of chemotherapy, but his disease showed few signs of improvement. Then, in July 2010, he enrolled in a clinical trial for an experimental treatment, designed to turn his own immune cells against his cancer. Months later, all signs of leukemia had vanished, his physicians report today
Levine and his colleagues designed a new gene that can be inserted into T cells to trick them into attacking cancerous B cells, the cause of chronic lymphocytic leukemia (CLL). The new gene encodes a receptor that, on one end, can bind to a molecule that's unique to cancerous B cells. The other end of the receptor sets off a chain reaction when such a B cell is bound, eventually leading the T cell to destroy the cancerous cell. "Essentially, we're converting T cells that would normally recognize other types of cells to be tumor specific," Levine says. ORIGINAL ARTICLE

Friday, August 19, 2011

IIM-A asks AYUSH to follow Chinese medicine example

AHMEDABAD: In a set of recommendations that Indian Institute of Management Ahmedabad (IIM-A) has given the ministry of health and family welfare's department of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy (AYUSH) recently, the latter has been suggested to learn from the Chinese examples. IIM-A recommended AYUSH introduce farming of medicinal herbs and commence mass scientific validation of medicines like the Chinese did.
ORIGINAL ARTICLE

Friday, August 12, 2011

Blood Donations from Men Who Have Sex with Other Men. Questions and Answers

Men who have had sex with other men are currently deferred as blood donors. To know more Visit;

Approval of Complera: emtricitabine/rilpivirine/tenofovir DF fixed dose combination

The FDA has approved a new fixed-dose combination — emtricitabine/rilpivirine/tenofovir DF (FTC/RPV/TDF) — for use in treatment-naive HIV-infected patients.
The treatment, marketed as Complera, is a single pill that should be taken once daily. The pill is contraindicated with some anticonvulsants, antimycobacterials, and proton-pump inhibitors (see the FDA alert for a full list).
Approval for the combination was based, in part, on data from previous phase III studies for rilpivirine, which the FDA approved in May. In his HIV and ID Observations blog, Dr. Paul Sax writes that data comparing rilpivirine with efavirenz demonstrate a trade-off between safety/tolerability (favoring rilpivirine) and efficacy (favoring efavirenz), and he wonders whether "this efficacy difference [will] be reduced now that the single-pill treatment is available — a question now being tested in an open-label clinical trial."
ORIGINAL ARTICLE

Tuesday, August 9, 2011

TB Rapid Test Performs Well in Children

Overall, the Xpert MTB/RIF assay demonstrated high sensitivity and specificity; in smear-negative cases, a second induced specimen increased sensitivity from 33% to 61%.
The Xpert MTB/RIF, a new molecular test to identify Mycobacterium tuberculosis and rifampin resistance, performs with high sensitivity and specificity in adult populations (JW Infect Dis Apr 27 2011). Might it also work well for children, in whom diagnosis is complicated by low numbers of mycobacteria and difficulty in obtaining good specimens?
Original Article

Tuesday, August 2, 2011

Study: HIV risks rise with some birth control

In what's being called the first research of its kind, a study found that HIV-infected women in Africa are more likely to spread the AIDS virus if they use hormone-based birth control.
The women studied were about twice as likely to transmit HIV if they were on the pill or taking a hormone shot like Depo-Provera, compared to those not on the such birth control. The research is the first to look at this question, according to Renee Heffron of the University of Washington, one of the researchers.
Their research also found that uninfected women were about twice as likely to catch AIDS virus from their infected partners if they were on hormonal contraception, compared to those who were not. That finding echoed a phenomenon seen in earlier studies.
The researchers checked to make sure there were no significant differences in condom use, sexual behavior or other factors that would account for the differences.
The research was presented Wednesday at a meeting in Rome of the International AIDS Society.
The researchers said the findings need to be confirmed in follow-up studies, and should not cause women to immediately change birth control practices.
The increased risk of HIV infection also must be balanced against the consequences of unintended pregnancy, which in Africa can include maternal mortality and financial squalor, they explained.
"Contraception is incredibly important to economic and social development of women and children worldwide," said Dr. Jared Baeten, another University of Washington researcher on the study team.
Hormone shots release progestin, which keep a woman's ovaries from releasing eggs and also thins the lining of the uterus. Birth control pills contain progestin or progestin and estrogen and work the same way.
It's not clear exactly how the hormones may help spread the virus, but the theoretical risk has been known from earlier studies. A Kenya study found an increase in HIV-infected cells in cervical tissue after women started using various hormonal contraception.
The new study was done from 2004 to 2010 in seven African countries — Kenya, Uganda, Rwanda, Botswana, Zambia, Tanzania and South Africa.
It included nearly 2,500 women with HIV whose male partners were not infected. About a third took hormonal contraception at least once. Most of them were on the shots, which are taken once every few months.
The men had a 2.61 percent chance of becoming infected in a year's time if their partner was on hormonal contraception. If not, their chances of infection were 1.51 percent.
The research team also looked at about 1,300 couples in which the men were infected but not the women. About 20 percent of the women were on hormonal contraception, mostly injections.
The study found those women had a 6.6 percent chance of becoming infected in a year, compared to 3.8 percent for woman not on that kind of birth control.

High court warns against use of ‘Dr’ without valid medical degree

CHENNAI: Putting a pause to the tug-of-war between physicians and physiotherapists over the use of the prefix 'Dr,' the Madras High Court has asked the authorities to take action against persons who use the prefix in their prescriptions and advertisements without a valid medical degree.
Passing orders on a writ petition filed by the Indian Medical Association's Quackery Eradication Committee, the first bench comprising Chief Justice HL Gokhale and Justice KK Sasidharan said the IMA must furnish details of people prescribing allopathic medicines and administering allopathic treatment and using the prefix 'Dr' to the authorities.
The IMA wanted the court to consider its two representations to the government, and to initiate criminal prosecution against paramedical technicians, practitioners and physiotherapists who prescribed allopathic medicine and used the prefix 'Doctor (Dr).'
The government pleader assured the court that the authorities would take necessary action in accordance with law.
The state government had passed an order last year that a physiotherapist cannot use the prefix 'Dr' and should not prescribe drugs. However, paramedics and physiotherapists have been maintaining that the use of the prefix 'Dr' is more a matter of courtesy rather than adherence to law.
Referring to a similar petition filed in the court by IMA a few weeks ago, the first bench said that on January 5 the court had asked the petitioner to furnish the names of persons who are practising medicine without any valid licence. The court also asked the authorities to take stringent action such persons on receiving any information.