Overall, the Xpert MTB/RIF assay demonstrated high sensitivity and specificity; in smear-negative cases, a second induced specimen increased sensitivity from 33% to 61%.
The Xpert MTB/RIF, a new molecular test to identify Mycobacterium tuberculosis and rifampin resistance, performs with high sensitivity and specificity in adult populations (JW Infect Dis Apr 27 2011). Might it also work well for children, in whom diagnosis is complicated by low numbers of mycobacteria and difficulty in obtaining good specimens?
Original Article
The Xpert MTB/RIF, a new molecular test to identify Mycobacterium tuberculosis and rifampin resistance, performs with high sensitivity and specificity in adult populations (JW Infect Dis Apr 27 2011). Might it also work well for children, in whom diagnosis is complicated by low numbers of mycobacteria and difficulty in obtaining good specimens?
Original Article
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