This breakthrough could advance HIV vaccine design as well as therapy for other diseases.
The antibodies prevent the HIV virus from infecting cells.
The two antibodies are actually produced naturally and found in the blood of HIV-positive people.
U.S. researchers have discovered two powerful antibodies that neutralize more than 90 percent of all known strains of the HIV virus in the lab, new research released Thursday showed.
Scientists from the National Institutes of Health discovered the antibodies, known as VRCO1 and VRCO2, that prevent most HIV strains from infecting human cells. The find is a potential breakthrough for advancing HIV vaccine design, and antibody therapy for other diseases.
The authors, whose work is published in the July 9 issue of Science, also were able to demonstrate how one of these disease-fighting proteins gets the job done.
"The discovery of these exceptionally broadly neutralizing antibodies to HIV and the structural analysis that explains how they work are exciting advances that will accelerate our efforts to find a preventive HIV vaccine for global use," said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health.
THE GIST
Two powerful antibodies neutralize 90 percent of all known HIV strains.The antibodies prevent the HIV virus from infecting cells.
The two antibodies are actually produced naturally and found in the blood of HIV-positive people.
U.S. researchers have discovered two powerful antibodies that neutralize more than 90 percent of all known strains of the HIV virus in the lab, new research released Thursday showed.
Scientists from the National Institutes of Health discovered the antibodies, known as VRCO1 and VRCO2, that prevent most HIV strains from infecting human cells. The find is a potential breakthrough for advancing HIV vaccine design, and antibody therapy for other diseases.
The authors, whose work is published in the July 9 issue of Science, also were able to demonstrate how one of these disease-fighting proteins gets the job done.
"The discovery of these exceptionally broadly neutralizing antibodies to HIV and the structural analysis that explains how they work are exciting advances that will accelerate our efforts to find a preventive HIV vaccine for global use," said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health.
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