Use of Heparin in Pregnancy May Have No Benefit

          A treatment that has been used for more than two decades to prevent thrombosis in pregnant women may not be as effective at preventing pregnancy-related complications after all. A study of pregnant women at high risk for developing thrombosis showed that low molecular weight heparin (LMWH) may actually not be effective in preventing clotting disorders. Published by The Lancet on July 24, the study was led by Marc Rodger, MD, Chief of Hematology at The Ottawa Hospital.

The authors of the editorial that accompanies the study point out that a lack of clear guidelines, coupled with the desire to avoid poor outcomes, could lead practitioners to treat despite the lack of evidence. The editorial goes on to anticipate that the study results may lead clinicians to discontinue using heparin in these patients but does cite some problems with the study, including the small sample size, the long length of time to recruit the participants, the lower-than expected number of adverse events, and the confounding use of aspirin in both groups. - See more at: http://www.obgyn.net/use-heparin-pregnancy-may-have-no-benefit#sthash.mezHUk3h.dpuf

           The authors of the editorial that accompanies the study point out that a lack of clear guidelines, coupled with the desire to avoid poor outcomes, could lead practitioners to treat despite the lack of evidence. The editorial goes on to anticipate that the study results may lead clinicians to discontinue using heparin in these patients but does cite some problems with the study, including the small sample size, the long length of time to recruit the participants, the lower-than expected number of adverse events, and the confounding use of aspirin in both groups. 

         More at  http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2814%2960793-5/abstract

A treatment that has been used for more than two decades to prevent thrombosis in pregnant women may not be as effective at preventing pregnancy-related complications after all. A study of pregnant women at high risk for developing thrombosis showed that low molecular weight heparin (LMWH) may actually not be effective in preventing clotting disorders. Published by The Lancet on July 24, the study was led by Marc Rodger, MD, Chief of Hematology at The Ottawa Hospital. - See more at: http://www.obgyn.net/use-heparin-pregnancy-may-have-no-benefit#sthash.mezHUk3h.dpuf

A treatment that has been used for more than two decades to prevent thrombosis in pregnant women may not be as effective at preventing pregnancy-related complications after all. A study of pregnant women at high risk for developing thrombosis showed that low molecular weight heparin (LMWH) may actually not be effective in preventing clotting disorders. Published by The Lancet on July 24, the study was led by Marc Rodger, MD, Chief of Hematology at The Ottawa Hospital. - See more at: http://www.obgyn.net/use-heparin-pregnancy-may-have-no-benefit#sthash.mezHUk3h.dpuf

A treatment that has been used for more than two decades to prevent thrombosis in pregnant women may not be as effective at preventing pregnancy-related complications after all. A study of pregnant women at high risk for developing thrombosis showed that low molecular weight heparin (LMWH) may actually not be effective in preventing clotting disorders. Published by The Lancet on July 24, the study was led by Marc Rodger, MD, Chief of Hematology at The Ottawa Hospital. - See more at: http://www.obgyn.net/use-heparin-pregnancy-may-have-no-benefit#sthash.mezHUk3h.dpuf

A treatment that has been used for more than two decades to prevent thrombosis in pregnant women may not be as effective at preventing pregnancy-related complications after all. A study of pregnant women at high risk for developing thrombosis showed that low molecular weight heparin (LMWH) may actually not be effective in preventing clotting disorders. Published by The Lancet on July 24, the study was led by Marc Rodger, MD, Chief of Hematology at The Ottawa Hospital. - See more at: http://www.obgyn.net/use-heparin-pregnancy-may-have-no-benefit#sthash.mezHUk3h.dpuf