An audit about labour induction, using prostaglandin, in women with a scarred uterus

Cogan A et al. – Induction of labour after a previous caesarean section is still controversial. This study aims to analyse, the maternal, foetal and neonatal complications in a population of women who have a uterine scar in relation to the mode of labour and delivery. Although no increase in maternal or perinatal outcome was observed in relation to prostaglandin–induced labour after caesarean section, the authors concluded that this study was too underpowered to exclude an increased risk.
Methods

• Retrospective analysis of collected data from all the singleton deliveries of patients with a scarred uterus (N = 798), admitted to the hospital between August 2006 and March 2009.

Results

• Among 798 singleton deliveries, 36.1 % had a spontaneous labour, 12.6 % a prostaglandin–induced labour and 2.9 % an ocytocin–induced labour, and 48.4 % had an elective caesarean section.
• The chance of delivering vaginally was respectively 84.4 % for those who had a spontaneous labour, 75.2 % for those who were induced using prostaglandin, 82.6 % after induction using ocytocin.
• There were eight uterine ruptures, four after spontaneous labour (1.4 %), two after prostaglandin induction (2 %) and two at the time of an iterative caesarean section (0.5 %).
• There were no differences between groups, except the risk of haemorrhage (17.4 % after spontaneously induced labour, 34.8 % after ocytocin, 17.8 % after prostaglandin and 44.6 % after iterative caesarean section; p < 0.005) and the neonatal admissions when analysed by intention to treat only (8.3 % after spontaneously induced labour, 9.1 % after ocytocin, 12 % after prostaglandin and 16.8 % after iterative caesarean section; p < 0.009).

.Archives of Gynecology and Obstetrics, 08/10/2012