Refractory Heartburn Treatment Algorithm
Mechanisms of Refractory Heartburn1
Mechanisms of Refractory Heartburn1
| • Reflux hypersensitivity • Functional heartburn • Poor compliance and/or adherence • Misdiagnosis of GERD • Existence of comorbidities • Differences in genotypes • Residual gastroesophageal reflux • Eosinophilic esophagitis • Autoimmune skin disorders |
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