As early as the 1920s, the Mayo Clinic included a “balanced diet”
among the therapeutic modalities used to treat patients admitted for
what was then called “chronic arthritis.”1 Today, questions about whether dietary factors might trigger rheumatoid arthritis
(RA) — and whether diet could play a role in relieving symptoms — are
of keen interest to patients affected by the disease, and are frequently
asked of rheumatologists.2
In a recent study led by Jeffrey Sparks, MD, a rheumatologist and clinical researcher at Brigham and Women's Hospital and Harvard Medical School in Boston, Massachusetts, women from 2 Nurses' Health Study cohorts — 79,988 in the Nurses' Health Study (NHS), that was conducted from 1984 to 2014 and 93,572 women in the NHSII, which was conducted from 1991 to 2013 — were followed prospectively to determine whether an inflammatory diet pattern was associated with the risk for incident RA.3 At baseline and at 4-year intervals, participants in the NHS completed food frequency questionnaires that assessed the intake of a variety of foods and beverages over the previous year and ranked the frequency of each one on a scale from never or <1 day.="" month="" nbsp="" p="" per="" servings="" to="">
Dr Sparks said that researching the effect of physical activity on RA risk was the next step in understanding the metabolic effects that go on prior to the development of RA. “That's a lifestyle factor that there's relatively less literature about. We'd also like to understand some of the biological effects of obesity prior to [RA], particularly how the actual molecules secreted by adipose cells could impact RA risk.”
In a recent study led by Jeffrey Sparks, MD, a rheumatologist and clinical researcher at Brigham and Women's Hospital and Harvard Medical School in Boston, Massachusetts, women from 2 Nurses' Health Study cohorts — 79,988 in the Nurses' Health Study (NHS), that was conducted from 1984 to 2014 and 93,572 women in the NHSII, which was conducted from 1991 to 2013 — were followed prospectively to determine whether an inflammatory diet pattern was associated with the risk for incident RA.3 At baseline and at 4-year intervals, participants in the NHS completed food frequency questionnaires that assessed the intake of a variety of foods and beverages over the previous year and ranked the frequency of each one on a scale from never or <1 day.="" month="" nbsp="" p="" per="" servings="" to="">
Dr Sparks said that researching the effect of physical activity on RA risk was the next step in understanding the metabolic effects that go on prior to the development of RA. “That's a lifestyle factor that there's relatively less literature about. We'd also like to understand some of the biological effects of obesity prior to [RA], particularly how the actual molecules secreted by adipose cells could impact RA risk.”
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